PRP (autologous blood)
The body's own growth factors for complexion and collagen stimulation
Face
from 349 €¹
Hair and scalp
for thicker hair and hair growth
from 349 €¹
Neck, décolleté or hands
from 349 €¹
Overview
What a biostimulator does differently than a filler
A biostimulator doesn’t fill anything. It sets a stimulus to which the skin responds by building its own collagen. That’s why the result doesn’t appear immediately but grows over weeks – in return, it looks very natural and lasts a long time.
On the body, this is especially interesting for the hands , where the skin gets thinner and looks uneven. If, on the other hand, it’s about lost volume on the back of the hand, Hyaluronic acid is the more direct route. Both can also be combined. An overview of all Body treatments can be found on the parent page. We assess in advance whether a biostimulator makes sense for you.
The most important information at a glance:
- During body biostimulation, an injectable active ingredient is applied that stimulates the skin to produce its own collagen.
- Unlike a filler, it does not create immediate volume but improves texture and firmness over weeks.
- The back of the hand is a particular problem on the body, where the skin becomes thin and the tendons and veins stand out more.
- The result builds gradually and lasts for a long time, usually about twelve to eighteen months.
- One to two sessions usually make sense; the individual items are listed in the price overview.
- Medically reviewed by Dr. med. Nora Bilir
- Internist
- 07.10.2026
- Medically reviewed by Dr. med. Nora Bilir
- Internist
- 07.10.2026
Guides
Why the skin rebuilds its own collagen
How Biostimulation works
Substances are injected that trigger a controlled reaction of the tissue itself. The body then forms new collagen over several weeks. The result builds up slowly and therefore looks particularly natural, because it comes from the body’s own tissue.
Application on the body
On the body, biostimulation is well suited for areas with thin, sagging skin. We often treat the Hands, where firmness and a softer skin texture are the focus.
Why multiple sessions are useful
Because the effect comes from collagen formation, several sessions a few weeks apart are usually needed. This way, the effect builds up step by step. We give you a precise estimate of the number of sessions after the assessment.
Procedure and follow-up
The treatment takes only a few minutes. Minor redness or slight swelling in the area are possible immediately afterwards and subside quickly. Often the area is gently massaged after the injection to distribute the material.
Durability
Because the body produces its own collagen, the results last relatively long, often over a year. After that, the treatment can be repeated. It is well suited as a supplement to other procedures that improve skin quality.
What sets us apart
Four good reasons for NOE.
Owned and managed by doctors
Permanent
medical team
Natural
Results
Detailed consultation
Costs
Price list
Price list
Skin, Regeneration & Biostimulators
Polynucleotides (salmon DNA)
Support skin regeneration and biostimulation – without volume
Eye area & lower lid
for sensitive skin on the lower eyelid
from 329 €¹
Face
from 329 €¹
Radiesse (Calcium hydroxylapatite, Biostimulator)
from 499 €¹
Juläine (polylactic acid, biostimulator)
from 799 €¹
Mesotherapy
upon request
¹ Billing according to the German Medical Fee Regulations (GOÄ).
Certified. Precise. Trustworthy.
Excellence in aesthetic medicine
Medically reviewed by
Dr. med. Nora Bilir
Internist
Additional qualification in Nutritional Medicine
Additional qualification
Nutritional Medicine
Nutritional Medicine
Founder & Medical Director
Member of DGBT & DGIM
Dr. med. Nora Bilir is a specialist in internal medicine with the additional qualification of nutritional medicine and specialization in minimally invasive aesthetic medicine and laser medicine. She is the founder and medical director of the NOE clinics in Hamburg. She has been practicing medicine since receiving her license to practice in 2014 and has performed more than 20,000 aesthetic treatments in over ten years. She received her doctorate in 2017 at the University of Hamburg (UKE) and is a member of the German Society for Internal Medicine (DGIM) and the German Society for Aesthetic Botulinum Toxin Therapy (DGBT). As a trainer and lecturer, she also trains physicians on behalf of an internationally leading manufacturer of aesthetic injection preparations.
On this page, she has verified the accuracy of all the medical information about wrinkle treatment with botulinum toxin – from its mechanism of action to the procedure, as well as the risks and duration of effect.
- Last reviewed on 09.07.2026
Three simple steps
How does a treatment work?
In a detailed consultation, we take the time to understand your wishes and ideas. Together, we develop an individual treatment strategy that is perfectly tailored to your needs. Transparency and trust are at the core of this process.
Your treatment will be carried out using state-of-the-art techniques and the highest precision. Our goal is to achieve natural and aesthetic results that enhance your personality. We place great importance on your well-being and a pleasant atmosphere throughout the entire process.
After the treatment, we continue to support you to optimally support the healing process. We are by your side with care instructions and answers to your questions. Your satisfaction and lasting results are our ultimate goal.
Appointment
Book your appointment!
Medical team
Who treats you
Who treats you
Dr. med. Chris Winter
General practitioner
Hamburg
Training in aesthetic medicine and laser medicine. Emphasis on tattoo removal, skin rejuvenation, and hair growth.
Reviews
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Insights into Our Practice
NOE clinics Hamburg-Uhlenhorst
Experience aesthetic medicine at its finest in one of Hamburg's most beautiful locations. State-of-the-art treatment methods, medical expertise, and an ambiance that will make you feel at home from the very first moment.
Why us?
THAT'S WHY NOE CLINICS
98 % SATISFIED PATIENTS
15,000+ TREATMENTS CARRIED OUT
100 % MEDICAL EXPERTISE
Do you have any questions?
FAQ / Frequently Asked Questions
What is biostimulation?
An injectable active ingredient triggers a stimulus in the skin that the body reacts to by building its own collagen. Therefore, no volume is introduced from the outside.
What is the difference from hyaluronic acid?
Hyaluronic acid works immediately and creates volume. A biostimulator works slowly and builds up the body’s own collagen. Depending on the goal, the two can be combined.
When will I see results?
The first changes become apparent after a few weeks. The full effect develops gradually over months.
How many sessions do I need?
Most often, several treatments at intervals of a few weeks are advisable. We will formulate the plan together after the assessment.
How much does a biostimulation cost?
You can find the current prices in the price list on this page. The price depends on the preparation, quantity and number of sessions.
Is there a downtime period?
Swelling, redness and small bruises at the injection sites are possible. The follow-up care, which includes a massage with some products, will be discussed on-site.
For whom is the treatment not suitable?
During pregnancy and lactation, in acute infections in the area, in a tendency to keloids, and in certain autoimmune diseases.